Journal: bioRxiv
Article Title: Nanoporous Microelectrodes for Neural Electrophysiology Recordings in Organotypic Culture
doi: 10.1101/2025.05.12.653414
Figure Lengend Snippet: Electrophysiology and biocompatibility of novel culture system. (a) High-impedance glass microelectrode recordings show well-defined multi-unit activity in a cultured brain slice in the presence of gabazine. (b) Low-impedance wire electrode recordings also show multi-unit activity with some rebound shot noise. (c) Cell counts show no significant difference in histology between control, nanocarbon and insulated nanocarbon conditions. (d) Example pad configuration (left) and brain slice in situ (right).
Article Snippet: To fabricate double side printed microelectrode schematics , the membrane substrates were pierced using tungsten micro needles (<1 μ m tip diameter, 125 μ m shaft diameter, World Precision Instruments).
Techniques: Activity Assay, Cell Culture, Slice Preparation, Control, In Situ